Ischaemic nephropathy secondary to atherosclerotic renal artery stenosis: clinical and histopathological correlates

Abstract

The severity of renal histopathological findings in patients who underwent nephrectomy for resistant hypertension correlated with an increased prevalence of cardiovascular disease, a greater degree of renal dysfunction and more severe dyslipidaemia. Statin therapy may affect development of intra-renal injury by slowing the progression of fibrosis.