Concepedia

Publication | Closed Access

Increased Circulating Nitrogen Oxides After Human Tumor Immunotherapy: Correlation With Toxic Hemodynamic Changes

DOI

129

Citations

0

References

1992

Year

Juan B. Ochoa, Brendan D. Curti, Andrew B. Peitzman, R L Simmons, Timothy R. Billiar, Robert P. Hoffman, Raymond Rault, DL Longo, Walter J. Urba, Augusto C. Ochoa
JNCI Journal of the National Cancer Institute

Abstract

Since .N = O synthesis can be competitively inhibited by L-arginine analogues, a possible pharmacologic modulation of .N = O production could potentially contribute to better management of toxic side effects seen in IL-2 cancer therapies.