Bacterial Mn²⁺Oxidizing Systems and Multicopper Oxidases: An Overview of Mechanisms and Functions

Abstract

Abstract Manganese is oxidized by a wide variety of bacteria. The current state of knowledge on mechanisms and functions of Mn2+ oxidation in two strains of Pseudomonas putida, in Leptothrix discophora SS-1, and in Bacillus sp. strain SG-1 is reviewed. In all three species, proteins bearing resemblance to multicopper oxidases appear to be involved in the oxidation process. A short description of the classification of Cu centers is followed by a more detailed review of properties and postulated functions of some well-known multicopper oxidases. Finally, suggestions are made for future research to assess the potential role of multicopper oxidases in bacterial Mn2+ oxidation. Keywords: Mn2 Oxidation;Multicopper Oxidases;Leptothrix Discophora;Pseudomonas Putida;Bacillus Sp. Sg-1