Separation of 9-Methoxycamptothecin and Camptothecin from Nothapodytes foetida by Semipreparative HPLC

S. C. Puri, G. Handa, Bilal A. Bhat, Vishal Gupta, Touseef Amna, Neeraj Kumar Verma, R. Anand, K.L. Dhar, Ghulam N. Qazi

Journal of Chromatographic Science · 2005 · 30 citations · 3 references

Concepts

Abstract

The present work describes the isolation of camptothecin and 9-methoxycamptothecin from the aerial parts of Nothapodytes foetida by semipreparative high-performance liquid chromatography because the separation of compounds by conventional procedures is tedious and cumbersome. The purity of the isolates is determined by physicochemical data and liquid chromatography-mass spectrometry.

References

3