Is controlled ovarian stimulation in intrauterine insemination an acceptable therapy in couples with unexplained non‐conception in the perspective of multiple pregnancies?

Abstract

In COS-IUI for unexplained non-conception, induction of more than one follicle did not improve the ongoing PR, but increased the risk of multiple pregnancies. Multiple PR remained high in the first four cycles with multifollicular stimulation. Therefore, in order to reduce the number of multiple pregnancies, in all IUI cycles for unexplained non-conception monofollicular growth should be aimed at.