Safety and Efficacy of Pimecrolimus in Atopic Dermatitis: A 5-Year Randomized Trial

Abstract

Long-term management of mild-to-moderate AD in infants with PIM or TCSs was safe without any effect on the immune system. PIM was steroid-sparing. The data suggest PIM had similar efficacy to TCS and support the use of PIM as a first-line treatment of mild-to-moderate AD in infants and children.