Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using <i>β</i>‐Cyclodextrin as a Catalyst in Water Under Neutral Conditions

Abstract

Abstract Synthesis of substituted pyrroles in H 2 O by using β ‐cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good‐to‐excellent yields (79–89%). The supramolecular catalysis of the reaction was studied using 1 H‐NMR spectroscopy. β ‐Cyclodextrin can be recovered and reused several times without loss of activity.