Journal of Clinical Oncology · 2006 · 131 citations · 47 references
In this large, prospective, multi-institutional study, RT-PCR analysis on SLNs and PBMCs provides no additional prognostic information beyond standard histopathologic analysis of SLNs. Detection of more than one marker in PBMC is associated with a worse prognosis. RT-PCR remains investigational and should not be used to direct adjuvant therapy at this time.
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The Orderly Progression of Melanoma Nodal Metastases
Douglas S. Reintgen, C. Wayne Cruse, Karen Wells et al. · Annals of Surgery · 1994 · 740 citations