Selective Intramolecular CH Amination through the Metalloradical Activation of Azides: Synthesis of 1,3‐Diamines under Neutral and Nonoxidative Conditions

Abstract

N2 is the only by-product in a stereospecific and highly diastereoselective intramolecular CH amination of sulfamoyl azides with a cobalt(II)-based metalloradical catalyst (see scheme). The catalytic system has an unusual capacity for the efficient amination of strong primary CH bonds, as well as secondary and tertiary CH bonds, and functional-group tolerance is excellent owing to the neutral and nonoxidative conditions. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.