High-Dose Atorvastatin Reloading Before Percutaneous Coronary Intervention Increased Circulating Endothelial Progenitor Cells and Reduced Inflammatory Cytokine Expression During the Perioperative Period

Abstract

Our results suggested that high-dose atorvastatin application before PCI triggered early EPC circulation. Furthermore, postoperative inflammatory cytokine sICAM-1 as well as hCRP serum levels were reduced, while postinterventional myocardial injury marker TnI elevations were inversely correlated with statin reloadings.