METHYL SALICYLATE FLUORESCENCE AS A PROBE OF THE GEOMETRY OF COMPLEXATION TO CYCLODEXTRINS

Abstract

Abstract Methyl salicylate (MS) is found to form complexes with α‐, β‐ and γ‐cyclodextrins in aqueous solution. The fluorescence of the complexes differ dramatically from that of MS in pure aqueous solution in the case of α‐ and γ‐cyclodextrin, but is similar to that of MS in pure aqueous solution in the case of β‐cyclodextrin. The binding constants for the complexes have been evaluated and the fluorescence of the complexes has been employed to infer the geometry of the complexes.