Effect of Estradiol and Progesterone on the Low‐Dose Endotoxin‐Induced Glomerular Inflammatory Response of the Female Rat

Abstract

It is concluded that endotoxin-induced monocyte infiltration and ICAM-1 expression are inhibited by a factor produced during the follicular phase, probably by developing follicles. Infiltration of neutrophils and expression of MAC-1, LFA-1, VLA-4 seem to be under control of progesterone or estradiol.