Methylation Markers for <i>CCNA1</i> and <i>C13ORF18</i> Are Strongly Associated with High-Grade Cervical Intraepithelial Neoplasia and Cervical Cancer in Cervical Scrapings - Concepedia

Concepedia

Publication | Open Access

Methylation Markers for <i>CCNA1</i> and <i>C13ORF18</i> Are Strongly Associated with High-Grade Cervical Intraepithelial Neoplasia and Cervical Cancer in Cervical Scrapings

DOI Full Paper Access

62

Citations

31

References

2009

Year

Nan Yang, Jasper J.H. Eijsink, Ágnes Lendvai, Haukeline H. Volders, Harry Klip, Henk J. Buikema, Bettien M. van Hemel, Ed Schuuring, Ate G.J. van der Zee, G. Bea A. Wisman

Cancer Epidemiology Biomarkers & Prevention

Abstract

Methylation of CCNA1 and C13ORF18 in cervical scrapings is strongly associated with CIN II or higher-grade lesions. Therefore, these markers might be used for direct referral to gynecologists for patients with a methylation-positive scraping.

References

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