TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth - Concepedia

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TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth

40

Citations

44

References

2007

Year

Leo Christopher DeRosier, Selwyn M. Vickers, Kurt R. Zinn, Zhi Huang, Wenquan Wang, William E. Grizzle, Jeffrey C. Sellers, Cecil R. Stockard, Tong Zhou, Patsy G. Oliver,

Molecular Cancer Therapeutics

Abstract

Pancreatic cancer cell lines express varying levels of DR5 and differ in their sensitivity to TRA-8 and gemcitabine-induced cytotoxicity. TRA-8 with two cycles of gemcitabine therapy produced the best overall survival.

References

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