Copper‐Mediated Amplification Allows Readout of Immunoassays by the Naked Eye

Abstract

An eye for color: Antibodies modified by CuO nanoparticles (NPs) are subjected to immunoreaction with the release of CuII, which can be detected by click chemistry. The Cu acts as a catalyst that induces aggregation of Au NPs functionalized with azide and alkyne groups, which can be seen as a color change (see picture). The detection of HIV in blood serum of infected patients is demonstrated. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.