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Novel Routes for the Synthesis of Upper Rim Amino and Methoxycarbonyl Functionalized Calix[4]arenes Carrying Other Types of Functional Groups
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1994
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Novel OrganocatalystsEnantioselective SynthesisEngineeringAmino Derivatives 3Functional GroupsOrganic ChemistryChemistryUpper RimHeterocycle ChemistryNatural Product SynthesisMethoxycarbonyl Functionalized CalixSynthetic ChemistryBiomolecular EngineeringUpper Rim AminoSelective Functionalization
The selective functionalization of calix[4]arenes 1 by iodination at the upper rim in the presence of other functionalities is described. The resulting (partly) iodinated calix[4]arenes 2 are good starting materials for the preparation of both the corresponding carboxylic ester and amino derivatives 3 and 6, respectively.