Concepedia

Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia

Cédric Le May, Sanae Kourimate, Cédric Langhi, Maud Chétiveaux, Anne Jarry, Christine Coméra, Xavier Collet, Folkert Kuipers, Michel Krempf, Bertrand Cariou,

Arteriosclerosis Thrombosis and Vascular Biology · 2009 · 161 citations · 24 references

DOIFull text

Open access

Abstract

These findings indicate that in addition to its effect on LDL-cholesterol, PCSK9 deficiency might protect against cardiovascular disease by reducing postprandial triglyceridemia.

References

24

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications · 1978 · 4.6K citations

, , +9

Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease

Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley et al. · New England Journal of Medicine · 2006 · 3.1K citations · Full text

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Marianne Abifadel, Mathilde Varret, Jean‐Pierre Rabès et al. · Nature Genetics · 2003 · 3K citations

, , +4

Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women

Børge G. Nordestgaard, Marianne Benn, Peter Schnohr et al. · JAMA · 2007 · 2K citations

Fasting Compared With Nonfasting Triglycerides and Risk of Cardiovascular Events in Women

Sandeep Bansal, Julie E. Buring, Nader Rifai et al. · JAMA · 2007 · 1.6K citations