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Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals

DOIFull Paper Access

83

Citations

16

References

2012

Year

Eleni Mylona, Maria Mouktaroudi, Tania O. Crișan, Stamatoula Makri, Aikaterini Pistiki, Marianna Georgitsi, Athina Savva, Mihai G. Netea, Jos WM van der Meer, Evangelos J. Giamarellos‐Bourboulis,
Arthritis Research & Therapy

Abstract

The synergy between MSU crystals and TLR-2 ligands is more prominent in patients with gout than in controls. This is likely mediated by the enhanced maturation of pro-IL-1β into IL-1β.

References

YearCitations

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