Concepedia

Oxaliplatin Combined With Weekly Bolus Fluorouracil and Leucovorin As Surgical Adjuvant Chemotherapy for Stage II and III Colon Cancer: Results From NSABP C-07

J. Philip Kuebler, H. Samuel Wieand, Michael J. O’Connell, Roy E. Smith, Linda H. Colangelo, Greg Yothers, Nicholas J. Petrelli, Michael Findlay, Thomas E. Seay, James N. Atkins,

Journal of Clinical Oncology · 2007 · 1K citations · 14 references

DOI Full text

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Abstract

The addition of oxaliplatin to weekly FULV significantly improved DFS in patients with stage II and III colon cancer. FLOX can be recommended as an effective option in clinical practice.

References

14

Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer

Thierry André, C. Boni, Lamia Mounedji-Boudiaf et al. · New England Journal of Medicine · 2004 · 3.6K citations · Full text

Levamisole and Fluorouracil for Adjuvant Therapy of Resected Colon Carcinoma

Charles G. Moertel, Thomas R. Fleming, John S. Macdonald et al. · New England Journal of Medicine · 1990 · 2.2K citations · Full text

Capecitabine as Adjuvant Treatment for Stage III Colon Cancer

Chris Twelves, A. Wong, Marek P. Nowacki et al. · New England Journal of Medicine · 2005 · 1.2K citations · Full text

Disease-Free Survival Versus Overall Survival As a Primary End Point for Adjuvant Colon Cancer Studies: Individual Patient Data From 20,898 Patients on 18 Randomized Trials

Daniel J. Sargent, Harry S. Wieand, Daniel G. Haller et al. · Journal of Clinical Oncology · 2005 · 702 citations · Full text

The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03.

Norman Wolmark, Howard E. Rockette, Bernard Fisher et al. · Journal of Clinical Oncology · 1993 · 686 citations