Concepedia

Thyroid Hormone Early Adjustment in Pregnancy (The THERAPY) Trial

Leila Yassa, Ellen Marqusee, Rachael L. Fawcett, Erik K. Alexander

The Journal of Clinical Endocrinology & Metabolism · 2010 · 254 citations · 20 references

DOIFull text

Open access

Abstract

A two-tablet increase in l-T(4) initiated at confirmation of pregnancy significantly reduces the risk of maternal hypothyroidism during the first trimester and mimics normal physiology. Monitoring TSH every 4 wk through midgestation is recommended.

References

20

Serum TSH, T<sub>4</sub>, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)

Joseph G. Hollowell, N Staehling, W. Dana Flanders et al. · The Journal of Clinical Endocrinology & Metabolism · 2002 · 3.8K citations

, , +17

The Colorado Thyroid Disease Prevalence Study

Gay J. Canaris, Neil Manowitz, Gilbert H. Mayor et al. · Archives of Internal Medicine · 2000 · 2.8K citations

Maternal Thyroid Deficiency during Pregnancy and Subsequent Neuropsychological Development of the Child

James E. Haddow, Glenn E. Palomaki, Walter C. Allan et al. · New England Journal of Medicine · 1999 · 2.6K citations · Full text

Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline

Marcos Abalovich, Nobuyuki Amino, Linda A. Barbour et al. · The Journal of Clinical Endocrinology & Metabolism · 2007 · 927 citations · Full text

Overt and Subclinical Hypothyroidism Complicating Pregnancy

Marcos Abalovich, Silvia Ortega‐Gutiérrez, Graciela Alcaraz et al. · Thyroid · 2002 · 704 citations

, , +15