Metallation of Ligands with Biological Activity: Synthesis and X‐ray Characterization of the New Sulfathiazolato Complexes of Gold(I) and Silver(I): [(sulfathiazolato)AuPPh₃] and [Ag(sulfathiazolato)]₂ (sulfathiazole = N¹‐2‐thiazolyl‐sulfanilamide)

Abstract

Abstract Sulfathiazole reacts with [Ph 3 PAu(CH 3 COO)] in benzene and with Ag(CH 3 COO) in methanol giving [(sulfathiazolato)AuPPh 3 ] ( 1 ) and {[Ag(sulfathiazolato)] 2 } n ( 2 ). While the lattice of 1 contains single molecules with linear N–Au–P bonds, compound 2 performs a polymeric, one‐dimensional assembling of [Ag(sulfathiazolato)] 2 dimers linked through intermolecular Ag···O=S=O interactions along the crystallographic axis b . The silver atoms achieve a tetrahedral configuration through Ag–Ag contacts which measure 2.8427(4) Å, considerably shorter than the normal bonding distance of metallic silver.