The effects of Ginger on spermatogenesis and sperm parameters of rat

Abstract

Background: Ginger rhizome (Zingiber officinale R., family:\nZingiberaceae) is used medicinally and as a culinary spice. Objective:\n Medicinal use of ginger dates back to ancient China and India. Ginger\nand its constituents are stated to have antiemetic, antithrombotic,\nantihepatotoxic, anti-inflammatory, stimulant, cholagogue and\nantioxidant. It has been used since ancient time as medicinal and food\norigins it contain antioxidative and androgenic activities and have\nwell effect in diseases treatment in more countries world-wide. As an\nantioxidant’s ginger has a useful effect on spermatogenesis and\nsperm parameters. Materials and Methods: Wistar male rat (n=30) were\nallocated into three groups, control (n=10) and test groups (n=20),\nthat subdivided into groups of 2 that received ginger rhizome powder\n(50 and 100mg/kg/day) for 20 consequence day. Animals were kept in\nstandard conditions. In twentieth day the testes tissue of Rats in\nwhole groups were removed and sperm was collected from epididymis and\nprepared for analysis. Results: Serum total testosterones significantly\nincreased in experimental group that has received 100 mg/kg/day Ginger\n(p<0.05) in comparison to control group. Besides, the percentage of\nsperm viability and motility in both test groups significantly\nincreased (p<0.05) in comparison to control group, Whereas, LH, FSH\nhormones, sperm concentration, morphology and testes weights in both\nexperimental and control group were similar. Conclusion: Results\nrevealed that administration of 100 mg/kg/day of ginger significantly\nincreased sperm percentage, viability, motility and serum total\ntestosterones. This suggested that ginger may be promising in enhancing\nsperm healthy parameters.