Infection Control and Hospital Epidemiology · 2009 · 65 citations · 9 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceAntimicrobial StewardshipMedical MicrobiologyAntibiotic ResistanceAntimicrobial Susceptibility TestingAntimicrobial TherapyDefinitive Antimicrobial TherapyEmpiric Antimicrobial TherapyUrinary Tract InfectionsAntimicrobial Resistance PatternsDrug Resistance PatternsEscherichia ColiNitrofurantoin TherapyOral Antibiotic TherapyTrimethoprim-sulfamethoxazole TherapyUrinary Tract Infection Antibiotic TherapyUrinary Tract Infection Empiric Therapy
In our study of nursing home residents with clinically suspected urinary tract infection who did not require the use of an indwelling catheter, we identified bacteria isolated from urine samples, the resistance patterns of these isolated bacteria, and the antibiotic therapy prescribed to the residents. Escherichia coli, the predominant organism isolated, frequently was resistant to commonly prescribed oral antibiotics. Trimethoprim-sulfamethoxazole remains the best empiric antimicrobial therapy for a urinary tract infection, but nitrofurantoin should be considered if E. coli is identified.
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Infectious Diseases Society of America
J. F. Enders · The Journal of Infectious Diseases · 1969 · 3.3K citations