p21/waf1/cip1 in Gastric Cancer: Associations with Histopathological Subtypes, Lymphonodal Metastasis, Prognosis and p53 Status

Abstract

These features show an association of p21 over-expression with certain clinico-pathological parameters of gastric cancer. In this context, our data suggest that p21 immunoreactivity in more than 5% of the tumour cells has a predictive value for the course of adenocarcinoma of the stomach.