Highly Active Chiral Ruthenium‐Based Metathesis Catalysts through a Monosubstitution in the N‐Heterocyclic Carbene

Abstract

Single (substitution) is better: New chiral ruthenium metathesis (pre)catalysts with a monosubstituted carbon atom in the N-heterocyclic carbene ligand are highly stable in solution, initiate easily, show very high enantioselectivity and excellent E selectivity in asymmetric ring-opening cross-metathesis (see scheme).