Light‐Induced Control of Protein Translocation by the SecYEG Complex

Abstract

Please close the pore! An organochemical photoswitch was introduced into two transmembrane segments that comprise the lateral gate of the bacterial-membrane-embedded protein-conducting pore. Reversible switching of the azobenzene between the trans and cis configurations by irradiation with visible and UV light enforced the opening and closure of the protein-conducting pore (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.