Vascular and Endovascular Surgery · 2007 · 65 citations · 53 references
Medical UltrasoundDiagnosisCeap ClassificationDermatologyThrombosisSkin Damage DueVenous ThrombosisVenous Disease TreatmentDuplex Ultrasound ImagingChronic Venous DiseasePublic HealthRadiologyCardiovascular ImagingVenous DiseaseUltrasoundVenous RefluxCardiovascular DiseaseSkin DamageMedicineAnesthesiology
Identified were characteristics of individuals with skin damage related to chronic venous disease. Patients with chronic venous disease (n = 164) were evaluated with duplex ultrasound imaging and were placed in classes 4, 5, and 6 according to the CEAP classification. Their findings were compared with 100 class 2 controls. The prevalence of deep venous thrombosis was higher in the study group (23.7%) versus controls (5.1%; P < .0001), as was the prevalence of deep, perforator, and combined patterns of disease (P < .0001, P < .0007, and P < .0001). The mean duration of disease in controls 2 was shorter compared with the study group (P = .0019). The prevalence of reflux and obstruction within the study group was higher than in controls (P = .0021). Skin changes accurately reflect severity of chronic venous disease. Superficial and perforator vein reflux is the major cause of disease.
53
The Long-Term Clinical Course of Acute Deep Venous Thrombosis
P. Prandoni · Annals of Internal Medicine · 1996 · 2.1K citations
Chronic ulceration of the leg: extent of the problem and provision of care.
M J Callam, C V Ruckley, D R Harper et al. · BMJ · 1985 · 729 citations · Full text
Causes of venous ulceration: a new hypothesis
Paul D. Smith, Philip Thomas, J H Scurr et al. · BMJ · 1988 · 563 citations · Full text
Definition of venous reflux in lower-extremity veins
Nicos Labropoulos, Jay Tiongson, Landon Pryor et al. · Journal of Vascular Surgery · 2003 · 457 citations