Hemodynamic Effects of the Angiotensin-Converting Enzyme Inhibitor, Ramipril, in Patients with Mild to Moderate Aortic Stenosis and Preserved Left Ventricular Function

Kevin D. O’Brien, Xue-Qiao Zhao, David M. Shavelle, Michael T. Caulfield, Rebecca Letterer, Samir Kapadia, Jeffrey L. Probstfield, Catherine M Otto

Journal of Investigative Medicine · 2004 · 93 citations · 0 references

Abstract

Short-term treatment with up to 7.5 mg twice daily of ramipril was well tolerated in patients with mild to moderate AS and preserved left ventricular function. A surprisingly high proportion of patients with documented AS were already receiving ACE inhibitors.