PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver - Concepedia

Concepedia

Publication | Open Access

PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver

DOI Full Paper Access

218

Citations

39

References

2015

Year

Annie Demers, Samaneh Samami, Benjamin Lauzier, Christine Des Rosiers, Émilienne T. Ngo Sock, Huy Ong, Gaétan Mayer

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our results demonstrate an important role of PCSK9 in modulating the function of CD36 and triglyceride metabolism. PCSK9-mediated CD36 degradation may serve to limit fatty acid uptake and triglyceride accumulation in tissues, such as the liver.

References

	Year	Citations

Page 1