Expression of CC Chemokines CCL2, CCL5, and CCL11 is Associated with Duration of Disease and Complications in Type-1 Diabetes: A Study on Iranian Diabetic Patients

Abstract

According to the results of our study, elevated levels of CCL5 and CCL11 are in parallel with decreased level of CCL2 and are useful tools in the differential diagnosis of T1D from other types of metabolic disorders. Elevated levels of these CC chemokines probably could be implicated as predictive factors for occurrence of T1D complications. These results may also re-emphasize the prominent therapeutic role(s) of these CC chemokines in control of either T1D or its associated complications.