Concepedia

Differential Gene Expression Profile in Omental Adipose Tissue in Women with Polycystic Ovary Syndrome

Marta Cortón, José I. Botella‐Carretero, Alberto Benguría, Gemma Villuendas, Ángel Zaballos, José L. San Millán, Héctor F. Escobar‐Morreale, Belén Peral

The Journal of Clinical Endocrinology & Metabolism · 2006 · 174 citations · 49 references

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Abstract

The differences in the gene expression profiles in visceral adipose tissue of PCOS patients compared with nonhyperandrogenic women involve multiple genes related to several biological pathways, suggesting that the involvement of abdominal obesity in the pathogenesis of PCOS is more ample than previously thought and is not restricted to the induction of insulin resistance.

References

49

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

, , +12

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

David R. Matthews, J P Hosker, A. Rudenski et al. · Diabetologia · 1985 · 31K citations · Full text

, , +13

In silico prediction of protein-protein interactions in human macrophages

Oussema Souiai, Fatma Z. Guerfali, Slimane Ben Miled et al. · BMC Research Notes · 2014 · 11K citations · Full text

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Rafael A. Irizarry · Biostatistics · 2003 · 10.6K citations · Full text

Significance analysis of microarrays applied to the ionizing radiation response

Virginia Goss Tusher, Robert Tibshirani, Gilbert Chu · Proceedings of the National Academy of Sciences · 2001 · 10.6K citations · Full text

, , +23