Lewis Acid Catalyzed Formal Intramolecular [3+2] Cross‐Cycloaddition of Cyclopropane 1,1‐Diesters with Alkenes: General and Efficient Strategy for Construction of Bridged [<i>n</i>.2.1] Carbocyclic Skeletons

Abstract

Carbon bridges: The title reaction has been successfully developed, and applied to the total synthesis of the tetracyclic diterpenoids phyllocladanol and phyllocladene. The method provides an efficient, general, and conceptually new strategy for the construction of structurally complex and diverse [n.2.1] carbocyclic skeletons (see scheme). As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.