Competitive flow arising from varying degrees of coronary artery stenosis affects the blood flow and the production of nitric oxide and endothelin in the internal mammary artery graft

Abstract

CF from the native LAD coronary artery can decrease the blood flow in the LIMA graft and even change the direction of the flow. These changes may impair the function of the LIMA graft and affect ET or NO production, which in turn may lead to early LIMA graft failure.