Plastic & Reconstructive Surgery · 2014 · 159 citations · 14 references
MedicinePlastic SurgerySurgeryMicrosurgeryReconstructive SurgeryTissue EngineeringAdipose TissueBreast AugmentationBreast ReconstructionBreast SurgeryMicrosurgical ReconstructionSoft Tissue ReconstructionFat Grafting Breast AugmentationFat HarvestingHigh-volume Fat TransferInterstitial Fluid DistributionInterstitial Fluid ExchangeLiposuction-assisted ReconstructionRecipient Site ReconstructionVolume Expansion Therapy
The authors describe the techniques that use the principles of fat grafting to allow them to successfully graft megavolumes (250-ml range) of autologous fat into breasts. The Brava external volume expansion device preoperatively increases the volume and vascularity of the recipient site. Low-pressure liposuction and minimal centrifugation are used to gently extract and purify the adipose tissue with minimal trauma. Even and diffuse reinjection of the fat increases graft-to-recipient interface and reduces interstitial fluid pressure. Postoperative Brava use protects the graft and acts as a three-dimensional immobilizing splint. By adhering to these techniques, we have been able to graft megavolumes of fat into the breasts of over 1000 patients and obtain substantial long-term volume retention.
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Textbook of Medical Physiology
Annals of Internal Medicine · 1966 · 9.8K citations
Life Sciences, Anatomy, Physiology +12
Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
Penney M. Gilbert, Karen Havenstrite, Klas E. G. Magnusson et al. · Science · 2010 · 1.6K citations · Full text