Synthesis of biomimetic polyamines

Abstract

Synthesis of methylated oligopropylamines by the stepwise repetition of reactions between methyl acrylate and amine, amidation and reduction of the resulting amide is reported. Longchain oligomers (average 15 nitrogen atoms) were obtained via condensation reactions utilising 1,3-dibromopropane. Three new acrylic monomers were prepared by reaction of oligopropylamines with acryloyl chloride. The synthesized amines and monomers are promising as model compounds for biosilicification reactions, as biologically active substances and as building blocks in organic and polymer chemistry.