MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

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Life Sciences, Bioinformatics, Molecular Biology +13

Executive Summary: Heart Disease and Stroke Statistics—2012 Update

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Medicine, Cardiology, Preventive Medicine +15

Identification of Renox, an NAD(P)H oxidase in kidney

Miklós Geiszt, Jeffrey B. Kopp, Péter Várnai et al. · Proceedings of the National Academy of Sciences · 2000 · 829 citations

Life Sciences, Molecular Biology, Physiology +17

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

Junya Kuroda, Tetsuro Ago, Shouji Matsushima et al. · Proceedings of the National Academy of Sciences · 2010 · 774 citations · Full text

Life Sciences, Cardiology, Physiology +17

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation

Lena Serrander, Laetitia Cartier, Karen Bedard et al. · Biochemical Journal · 2007 · 620 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14