Allopurinol Attenuates Left Ventricular Remodeling and Dysfunction After Experimental Myocardial Infarction

Abstract

The present study reveals a novel beneficial effect of treatment with allopurinol, ie, a marked attenuation of LV remodeling processes and dysfunction after experimental MI. Allopurinol treatment therefore represents a potential novel strategy to prevent LV remodeling and dysfunction after MI.