Acta Medica Scandinavica · 1968 · 29 citations · 19 references
PharmacyPharmacologyPharmacotherapyCardiovascular PharmacotherapyHemodynamic ManagementRenal PharmacotherapyBlood Pressure ManagementEdemaHypertension ControlHypertension ManagementHypertension PharmacotherapyHypertensive Heart DiseaseAntihypertensive PharmacologyBlood PressureBlood Volume AssessmentBody Weight RegulationExchangeable Sodium EffectsExchangeable Sodium EstimationExchangeable Sodium Measurement
Abstract Blood volume, exchangeable sodium, body weight and blood pressure were studied in ten hypertensive patients after 14 days of therapy with alpha‐methyl‐dopa (Aldomet®). There was a significant increase in blood volume and a significant decrease in blood pressure. Changes in exchangeable sodium and body weight were small and non‐significant. One patient, however, developed cardiac pulmonary edema after one week of therapy.
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D.D. MUNRO · The Lancet · 1959 · 142 citations
Medicine, Dermatology, Immunology +13
METHYLDOPA IN HYPERTENSION CLINICAL AND PHARMACOLOGICAL STUDIES
C. T. Dollery, M. Harington · The Lancet · 1962 · 131 citations