Antibiotic regimens in severe and acute purulent exacerbations of chronic bronchitis.

Abstract

Purulent exacerbations of chronic bronchitis are usually treated with antibiotics.Tetracycline, penicillin with strepto- mycin, and ampicillin are those most often used.Though innumerable courses of these drugs have been given in this illness, no comparative trial of their efficacy has ever been made (Stuart-Harris, 1966).We report a randomized and " blindly " assessed comparison of these antibiotics in hospital inpatients, all of whom were moderately or severely ill.* Patients withdrawn because of deterioration oer side-effects.