Human Breast Cancer Cells Harboring a Gatekeeper T798M Mutation in HER2 Overexpress EGFR Ligands and Are Sensitive to Dual Inhibition of EGFR and HER2 - Concepedia

Concepedia

Publication | Open Access

Human Breast Cancer Cells Harboring a Gatekeeper T798M Mutation in HER2 Overexpress EGFR Ligands and Are Sensitive to Dual Inhibition of EGFR and HER2

DOI Full Paper Access

76

Citations

50

References

2013

Year

Brent N. Rexer, Ritwik Ghosh, Archana Narasanna, Mónica V. Estrada, Anindita Chakrabarty, Youngchul Song, Jeffrey A. Engelman, Carlos L. Arteaga

Clinical Cancer Research

Abstract

Simultaneous blockade of HER2 and EGFR should be an effective treatment strategy against HER2 gene-amplified breast cancer cells harboring T798M mutant alleles.

References

	Year	Citations

Page 1