Expression of Matrix Metalloproteinases in Supraglottic Carcinoma and Its Clinical Implication for Estimating Lymph Node Metastases

Abstract

Expressions of MMP-2, MMP-7, and MMP-9 are up-regulated in supraglottic carcinoma tissues, suggesting that MMPs may be useful in the detection of occult lymph node metastasis but that more research is needed.