A Method for Determining Minimum Alveolar Concentration of Anesthetic in the Rat

Abstract

Minimum alveclir concentrations (MAC) for halothane and methoxyflurane were determined at two stimulus intensities in the rat. Forty-three rats were anesthetized with halothane or methoxyflurane in oxygen, and after tracheostomy were ventilated with a Harvard Rodent Respirator. Anesthetic agents wer