Multiple Assembly Pathways Underlie Amyloid-β Fibril Polymorphisms

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.1K citations

Neurodegenerative Diseases, Alzheimer's Disease, Immunology +7

Thioflavine T interaction with synthetic Alzheimer's disease <i>β</i>‐amyloid peptides: Detection of amyloid aggregation in solution

Harry LeVine · Protein Science · 1993 · 2.2K citations · Full text

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

Aneta T. Petkova, Richard D. Leapman, Zhihong Guo et al. · Science · 2005 · 1.7K citations

Neurodegenerative Diseases, Alzheimer's Disease, Electron Microscopy +13

Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Gal Bitan, Marina Kirkitadze, Aleksey Lomakin et al. · Proceedings of the National Academy of Sciences · 2002 · 1.3K citations · Full text

Protein Assembly, Molecular Biology, Neurochemical Biomarkers +19