Randomized Clinical Trial of the Iron-Based Phosphate Binder PA21 in Hemodialysis Patients

Abstract

PA21 5-12.5 g/d significantly reduces serum phosphorus in hemodialysis patients. The 5 g/d and 7.5 g/d dosages showed similar efficacy to 4.8 g/d of sevelamer-HCl. The adverse events rate was similar for PA21 and sevelamer-HCl.