Albright's Syndrome Presenting as Thyrotoxicosis: Follow-up of a Case

Abstract

In 1937, Albright and colleagues1 reported a syndrome triad consisting of precocious puberty, cutaneous pigmentation, and polyostotic fibrous dysplasia of bones. More recently, a number of hormone excess endocrinopathies have been described as part of the syndrome, as reviewed by Hall and Warrick2 and DiGeorge.3 The reason for the autonomous functioning of diverse endocrine glands remains unknown. In 1970, Levitsky et al1 reported in this journal a 7-month-old who at that early age had symptoms of severe thyrotoxicosis. The purpose of this report is to present a follow-up of this interesting patient, in whom there developed findings consistent with Albright's syndrome.