Changes in serum cystatin C, creatinine, and C‐reactive protein after cardiopulmonary bypass in patients with normal preoperative kidney function

Abstract

Serum creatinine and cystatin C appear not to be interchangeable biomarkers during and immediately after CPB. Processes unrelated to kidney function such as acute inflammation have a significant effect on post-CPB changes in these biomarkers, and may result in significant increases in serum cystatin C that could erroneously be interpreted as AKI.