Targeted Expression of Anthrax Protective Antigen by <i>Lactobacillus Gasseri</i> as an Anthrax Vaccine

Abstract

Lactobacillus-based delivery offers tremendous practical advantages. Recombinant antigens such as PA would not require chemical coupling agents, and the recombinant bacteria can be administered orally where upon both mucosal and systemic immune responses are elicited.