Tetra-butylphosphonium arginine-based ionic liquid-promoted cyclization of 2-aminobenzonitrile with carbon dioxide

Abstract

Tetra-butylphosphonium arginine-based IL able to activate both amino-groups and CO₂ proved to be an efficient and recyclable catalyst for the synthesis of quinazoline-2,4(1<italic>H</italic>,3<italic>H</italic>)-diones from 2-aminobenzonitriles and CO₂ under solvent-free conditions.