Interactive Cardiovascular and Thoracic Surgery · 2004 · 24 citations · 16 references
MedicineAnesthesiologySurgeryAnesthesiaCardiothoracic AnesthesiologyCardiothoracic SurgeryAntiarrhythmic TherapyArrhythmia PharmacotherapyAtrial FibrillationCardiac MedicationsThoracic SurgeryThromboembolism PreventionBest Evidence SynthesisClinical Question AnsweringPerioperative Arrhythmia ManagementPerioperative Thoracic AnesthesiaPostoperative Arrhythmia PreventionProphylaxis In Thoracic SurgeryRandomized Clinical TrialsSurgical Arrhythmia Management
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed whether prophylactic anti-arrhythmic drugs may prevent atrial fibrillation (AF) following lung resection. Altogether 457 papers were found using the reported search, of which 14 presented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. We identified single randomized trials that have demonstrated a benefit for Diltiazem, Bupivacaine epidural and magnesium for prophylaxis against AF in patients undergoing non-cardiac thoracic surgery, with a number needed to treat of between 4 and 8 with these regimes.
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Amiodarone and the Development of ARDS After Lung Surgery
W. Van Mieghem, L. Coolen, Ines Malysse et al. · CHEST Journal · 1994 · 203 citations
Medicine, Pharmacotherapy, Surgery +12