Concepedia

Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes

V. M. S. Copping, Caroline J. Barelle, Bernhard Hube, Neil A. R. Gow, Alistair J. P. Brown, Frank C. Odds

Journal of Antimicrobial Chemotherapy · 2005 · 113 citations · 21 references

DOI

Abstract

Antifungal agents with three different mechanisms of action similarly generate a rise in expression of SAP2 and activity of the secreted Sap2 gene product, a known virulence factor, in most isolates of C. albicans. One isolate of the fungus showed an opposite response.

References

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